NC3Rs launches their 2017 CRACK IT Challenges

The NC3Rs is launching the 2017 CRACK IT Challenges* competition at an event in central London on 7 September 2017.

The 2017 CRACK IT Challenges competition consists of three Challenges identified jointly by the NC3Rs and Sponsors. There are three Sponsors: Shell, Syngenta and Unilever.

The Challenges This year there are three Challenges:
 
  • Challenge 26: “DARTpaths”: Mapping developmental and reproductive toxicity (DART) genes andpathways for cross-species comparison of toxic compound effects (Two Phase Challenge Sponsoredby Shell and Syngenta).
  • Challenge 27: “DoCE (Dosing for Controlled Exposure)”: Dosing strategies for characterising invitro dose-responses with increased relevance for in vivo extrapolation. (Two Phase ChallengeSponsored by Unilever and Shell).
  • Challenge 28: “RespiraTox”: In silico model for predicting human respiratory irritation. (SinglePhase Challenge Sponsored by Shell).

Full Challenge briefs describing the challenge, deliverables, in-kind contributions from the Sponsors and budget are available to view on the CRACK IT website.

The total budget available across the three Challenges is £2.7 million.
 
Each of the Challenges offers:
  • Funding.
  • A research contract.
  • In-kind contributions such as data, compounds and expertise from Sponsors.

The Competition

CRACK IT Challenges is a milestone-driven funding competition from the NC3Rs which is designed to:
  • Minimise the use of animals in research.
  • Support the development of marketable products and/or improved business processes.

Launch Event

We are hosting an event to launch the competition in central London on 7 September 2017, providing access to potential new partners and to the Challenge Sponsors to begin the discussions necessary to put together a winning application.
This event is free to attend but registration is essential. The deadline for registration is 1 September 2017